Won-Young Choi is an assistant professor in the Department of Pathology at the University of Tennessee Health Science Center. He is part of the University of Tennessee-Oak Ridge Innovation Institute’s Radiopharmaceutical Therapies Convergent Research Initiative. 

Choi’s primary research interest lies in understanding the regulatory mechanisms of cancer models by analyzing diverse epigenomic data, such as ATAC-seq, ChIP-seq, and Hi-C. As part of the CRI-DART project, Choi is investigating the mechanisms of radio-resistance in ovarian cancer patients. This work involves collaborating with experts in cell-based experiments and mouse models, generating single-cell transcriptomic and chromatin accessibility data to identify key mechanisms underlying radio-resistance. Ultimately, his goal is to propose potential targets for radiopharmaceutical therapy.

During his postdoctoral training, his research focused on developing computational methodologies using various sequencing data, including RNA-seq and ATAC-seq. Choi worked on multiple projects, ranging from detecting gene expression status to identifying alternative isoforms specific to cancer patients.

Education